Presumed dead, Lois returns to name Stewie as the person who tried to kill her. On the look out for Stewie, Joe leads a manhunt around Quahog. Determined to take over the world again, Stewie does whatever he can to become supreme ruler of the world. Desperate to stop Stewie, Lois realizes what she must do.

Lois and Peter sail off on a cruise. Jealous that he was left behind, Stewie's matricidal tendencies are rekindled. When Brian challenges him to actually do it, Stewie carries out his diabolical plan.

Peter starts an anti-immigration group; however, he quickly changes his mind when he finds out that he was born in Mexico. Unable to prove his citizenship, pass the naturalization test or convince investigators that his marriage to Lois is for real, he ends up working for Carter as a landscaper, all the while fighting for immigration rights.

James Woods returns to seek revenge against Peter. James Woods finds Peter's wallet, which he lost at Barry Manilow concert, and proceeds to steal Peter's identity, and his family. Peter decides to ruin James' career and image.

James Woods returns to seek revenge against Peter. James Woods finds Peter's wallet, which he lost at Barry Manilow concert, and proceeds to steal Peter's identity, and his family. Peter decides to ruin James' career and image.

Brian, afraid that he may have lost his last chance at love, searches for a former flame, Tracy. To his surprise, he discovers that he is the father to her son, Dylan. Tracy decides that Brian should raise the boy, and she drops him off at the Griffin's house. When Dylan runs rough-shot in the house, Brian's attitude towards parenting doesn't settle too well with Lois and Peter.

When Peter gets a pet parrot, he begins acting like a pirate. Peter accidentally kills the bird after raising hell through all of Quahog. Meanwhile, when Brian is visiting the vet, Chris falls in love with the intern, Anna.